Does Vyvanse help depression? We’ll examine the drug’s side effects and compare it to a placebo. We’ll also consider the drug’s adverse effects. Listed below are some of the more common adverse reactions associated with Vyvanse. For the most complete answer, consult your doctor. During your doctor’s visit, you may want to discuss your condition with a mental health professional.
Side effects of Vyvanse on depression
Although the benefits of Vyvanse on depression are numerous, there are some negative side effects as well. This medication can lead to dependence and abuse, and can even worsen existing depressive symptoms. It is also a Schedule II controlled substance, which means that it has a high potential for abuse. In addition, Vyvanse is addictive and can lead to stimulant psychosis if misused.
The FDA has not approved Vyvanse, but studies suggest that it may be helpful for patients with treatment-resistant depression or who have comorbid conditions, such as ADHD, binge eating disorder, and executive dysfunction. Although Vyvanse has a few negative side effects, it is recommended for patients with depression or a history of substance abuse. The drug also increases dopamine, which is thought to help people with depression.
Although Vyvanse is an effective treatment for depression, it has some serious side effects. While it is effective in treating attention deficit hyperactivity disorder, it can lead to a physical dependence. It can even lead to fatal overdose. Although the U.S. Department of Justice fined the manufacturer of Vyvanse $56.5 million for marketing the drug incorrectly, the dangers of abuse are real.
Comparison of Vyvanse to placebo
In a recent study, researchers compared the effectiveness of the antidepressant Vyvanse with a placebo. The study involved a crossover design, with subjects randomly assigned to placebo or Lisdexamfetamine Dimesylate (Vyvanse) for the first four weeks of treatment. The treatment groups were separated by two weeks of washout. In the placebo group, no adverse events were reported in more than one-third of patients, including headache, decreased appetite, and tachycardia.
In the first study, subjects taking Vyvanse experienced a 6.1-point reduction in MADRS total scores. They received the placebo treatment for the second study, where the difference was 7.3 points. Both groups experienced fewer rebound effects. Compared to placebo, Vyvanse reduced the severity of depressive symptoms more than the placebo. In both studies, the participants were more likely to be satisfied with the results than the placebo group.
The two-arm trial included 426 adults and 404 adults. The primary efficacy endpoint was the change in MADRS total scores from baseline to Week 16. Neither Vyvanse nor placebo met this endpoint. The trials were conducted in a variety of psychiatric conditions, such as depression, but not ADHD. The study also failed to show that either drug reduced the risk of suicide and the incidence of suicidal thoughts.
Adverse reactions to Vyvanse
Before starting any new medication, it is important to understand what side effects Vyvanse can cause. While it is not dangerous, Vyvanse may increase your risk of dependence. Do not take Vyvanse in larger amounts than recommended by your doctor, and make sure to take it at the same time every day. The medication should be taken orally and taken with food. It should not be taken after midnight. Do not share the medication with other people, especially if you have a history of drug abuse. Always disclose to your healthcare provider any other medical conditions you may have, including alcoholism or substance abuse.
People taking Vyvanse should monitor for signs of serotonin syndrome, which may lead to seizures. Serotonin syndrome may also lead to loss of coordination, high body temperature, and tremors. If you notice any of these symptoms, stop taking Vyvanse immediately and visit your HCP or the nearest hospital ER. Severe, life-threatening serotonin syndrome can cause seizures or tremors and should be treated with caution.
Other adverse reactions to Vyvanse and depression include: increased risk of serotonin syndrome. People who are allergic to lisdexamfetamine should not take it. People who have recently used MAO inhibitors such as isocarboxazid, phenelzine, and fluoxetine should avoid these medications while taking Vyvanse. While the majority of these symptoms are transient, they should be investigated as soon as possible.